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New approach to
calcification disorders

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Who we are

Sanifit is a clinical-stage biopharmaceutical company focused on treatments for progressive vascular calcification disorders. The company is a spin-off from the University of the Balearic Islands, and has offices in Spain and the U.S. Sanifit’s lead compound, SNF472, is a novel small molecule, and a selective and potent inhibitor of hydroxyapatite (HAP) crystallization, the final common pathway that leads to vascular calcification. Its clinical development is focused on two indications in End Stage Kidney Disease (ESKD) patients; calciphylaxis and peripheral artery disease (PAD).

The company conducted a Phase 2b trial (CaLIPSO) to assess the effect of SNF472 on slowing arterial calcification, a major risk factor for cardiovascular diseases in patients on dialysis. The trial met its primary endpoint in reducing coronary artery calcium progression in patients treated with SNF472 compared to patients receiving placebo over a 52-week period.

SNF472 is in Phase 3 clinical development for the treatment of calciphylaxis or CUA (calcific uremic arteriolopathy) in ESKD patients that will measure two alternate primary endpoints – wound healing and pain. SNF472 is orphan designated for the treatment of calciphylaxis by FDA and EMA.

A phase 3 trial in Peripheral Arterial Disease in ESKD will launch in 2021. PAD in ESKD is driven by progressive calcification of peripheral arteries and disease progression can lead to reduced walking ability, claudication and amputations.

Leadership

Mr. Antonio Jiménez

General Counsel & VP Operations

 Dr. Claire Padgett

SVP Development Operations

 Dr. Marco Antonio Moreno

VP Manufacturing

Mr. Hans Christian Keller

VP Business Development

 Ms. Marisa Guitart

Head of Business Operations

Board of directors

Russell G. Greig

Chairman of the Board

Joan Perelló

Managing Director

Pablo Cironi

Board Member

Joël Jean-Mairet

Board Member

Casper Breum

 Board Member

Geert-Jan Mulder

Board Member

Keith R. Leonard

Board Member

Damià Tormo

Board Member

Guy Paul Nohra

 Board Member

Juan Bárcenas - Board member

Juan Bárcena

 Board Member

Funding

Sanifit is backed by a strong syndicate of international investors. These investors include Venture Capital Funds, Corporate Venture Funds and several private investors (Invenzia, Toni and Guillem Ballester, Nefrona Foundation, Somtobir and several ex Phadia and ex Pharmacia employees and directors) represented by MGA.
To date, the company has raised over $130 million equity. The Company ’s main investors include:

Private investors

Public Funds

Número de proyecto: RTC-2014-2460-1
Título: RETOS COLABORACION
Nombre del Ministerio: Ministerio de Ciencia, Innovación y Universidades

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    CONTACT

    Sanifit


    SPAIN
    ParcBIT – Ctra Valldemossa km7.4
    Building Europa, 2nd floor
    07121 Palma

     

     +34 971 439 925
     info@sanifit.com

    USA
    3655 Nobel Drive
    Suite #540
    San Diego, CA 92122

    Sanifit ParcBIT – Ctra Valldemossa km7.4
    Building Europa, 2nd floor
    07121, Palma de Mallorca (Illes Balears)
    Sanifit USA - 3655 Nobel Drive Suite #540
    San Diego, CA 92122